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Verified by Psychology Today. Integrative Mental Health Care. This is the fifth post in a series on non-pharmacologic treatments of bipolar disorder. However, many individuals who benefit from lithium therapy discontinue this treatment because of adverse effects including weight gain, tremor, hair loss and thyroid problems. A few small studies have been done on trace lithium supplementation in bipolar disorder. In a 4-week study 24 subjects randomized to a small daily dose of lithium micrograms versus placebo reported sustained improvement in mood. Some studies report reduced risk among women only, while other studies report reduced risk among men only. Unfortunately, opinions on the effectiveness of lithium orotate are largely based on case reports. Most studies on lithium orotate have been done in rats, and very few human trials have been conducted. One animal study reported toxic effects of lithium orotate on the kidneys however critics argue that renal toxicity may have been due to relatively high doses administered to rats that do not reflect recommended doses in humans.

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Lithium is an element that, at the present time, is considered non-essential to the human body. However, it is getting a lot of attention as a therapy, and there are interesting reports of beneficial actions of lithium. It is also coming up with frequency because of increasing awareness on mental health issues.

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Robert (taken for 3 to 6 years) 15.01.2017

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