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Oral biguanide antidiabetic agent Used for type 2 DM in adult and pediatric patients 10 years and older; initial drug of choice Risk of lactic acidosis is low but requires care in prescribing and monitoring. Initially, mg PO twice daily or mg PO once daily, given with meals. In the geriatric adult, do not initiate therapy if 80 years old or older unless normal renal function is documented. Patients can also be titrated from mg PO twice daily to mg PO twice daily after 2 weeks. In the geriatric adult, do not titrate to the maximum dosage. Further adjustment should be individualized based on glucose-lowering response. If needed, increase the daily dosage by mg at weekly intervals. When given with an insulin secretagogue e. Max: 2, mg PO once daily at the evening meal. Titrate in increments of mg weekly as needed.

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Not enough data were available at that time to determine the relative risk of death or of death from heart disease. The discomfort can often be avoided by beginning at a low dose 1. In healthy individuals, this slight excess is cleared by other mechanisms including uptake by unimpaired kidneys, and no significant elevation in blood levels of lactate occurs. Extracorporeal treatments are recommended in severe overdoses. Chromatographic techniques are commonly employed. Anticholinergic drugs reduce gastric motility, prolonging the time drugs spend in the gastrointestinal tract.

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Most commonly, vomiting. Suspend therapy if dehydration occurs or before surgery.

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Adjunctive therapy to diet and exercise to improve glycemic control in adults with type 2 diabetes. Elderly patients are more likely to have decreased renal function; contraindicated in patients with renal impairment, carefully monitor renal function in the elderly and use with caution as age increases.

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It helps to control blood sugar. Treatment is combined with diet and exercise.

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It is used with a proper diet and exercise program and may be combined with other diabetes medications. This medication also decreases the amount of sugar made by your liver and absorbed by your stomach or intestines.

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Over half of all prescribed medications are for generic medications. Please allow 2 weeks for shipments to the United States and 4 weeks for other destinations.

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