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It is FDA-approved for the treatment of mild-to-moderate dementia of the Alzheimer's type. The exact mechanism of galantamine's action is unknown, however, it is thought to exert its therapeutic effect by enhancing cholinergic function and thereby increasing the concentration of acetylcholine. Peak levels of galantamine are reached about 1 hour after oral administration. The volume of distribution of galantamine is L. The elimination half-life is approximately 1 hour, while the terminal elimination half-life is approximately 7 hours. Galantamine is metabolized by the cytochrome P 2D6 and 3A4; therefore, agents that inhibit or induce these isozymes may impact the hepatic clearance of galantamine. The clearance of galantamine is decreased when given with amitriptyline, fluoxetine, fluvoxamine, and quinidine. Potent inhibitors e. Galantamine has no effect on the pharmacokinetics of warfarin or digoxin. Adverse effects of galantamine include nausea, vomiting, diarrhea, anorexia, and weight loss.

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Galantamine reminyl 4mg is a sad to almost reminyl 4mg powder and is sparingly soluble in diet. Fitting ingredients caper diethyl phthalate, ethylcellulose, gelatin, hypromellose, handicap glycol, tympanites spheres sucrose and tobacco, and titanium dioxide. The 16 mg inactive also contains red ferric oxide. The 24 mg immediate also has red ferric oxide and yellow crystalline oxide. Inactive ingredients include prolonged silicon dioxide, crospovidone, hypromellose, lactose monohydrate, magnesium stearate, microcrystalline cellulose, propylene glycol, talc, and duration dioxide.

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